\u00c7ocuklar\u0131 ast\u0131m ve alerjiden koruyan \u201c\u00e7iftlik etkisinin\u201d s\u0131rr\u0131 \u00e7\u00f6z\u00fcld\u00fc konusunda dikkat \u00e7eken geli\u015fmeler ya\u015fan\u0131yor.<\/p>\n
G\u00fcncelleme Tarihi: A\u011fustos 03, 2026 14:31 \u00c7iftliklerde b\u00fcy\u00fcyen \u00e7ocuklarda ast\u0131m, saman nezlesi ve egzama gibi hastal\u0131klar\u0131n daha az g\u00f6r\u00fclmesinin nedeni y\u0131llard\u0131r ara\u015ft\u0131r\u0131l\u0131yordu. Bilim insanlar\u0131, bu do\u011fal koruyucu etkinin arkas\u0131nda bulunabilecek dokuz bakteri t\u00fcr\u00fcn\u00fc belirledi. Ancak ara\u015ft\u0131rma hen\u00fcz bu bakterilerin hastal\u0131klar\u0131 do\u011frudan \u00f6nledi\u011fini kan\u0131tlam\u0131yor.<\/p>\n
\u00c7ocuklar\u0131n ba\u011f\u0131\u015f\u0131kl\u0131k sistemlerinin sa\u011fl\u0131kl\u0131 bi\u00e7imde geli\u015febilmesi i\u00e7in \u00e7evredeki farkl\u0131 mikroorganizmalarla temas etmesi gerekti\u011fi d\u00fc\u015f\u00fcncesi uzun s\u00fcredir bilim d\u00fcnyas\u0131nda tart\u0131\u015f\u0131l\u0131yor. \u201cHijyen hipotezi\u201d olarak bilinen bu yakla\u015f\u0131ma g\u00f6re a\u015f\u0131r\u0131 temiz ve mikroorganizmalardan ar\u0131nd\u0131r\u0131lm\u0131\u015f ortamlarda b\u00fcy\u00fcmek, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin zarars\u0131z maddelere kar\u015f\u0131 a\u015f\u0131r\u0131 tepki verme ihtimalini art\u0131rabiliyor. Ara\u015ft\u0131rmac\u0131lar, sanayile\u015fmi\u015f \u00fclkelerde \u00e7ocukluk \u00e7a\u011f\u0131 alerjileri, ast\u0131m, saman nezlesi ve egzama vakalar\u0131 artarken \u00e7iftliklerde b\u00fcy\u00fcyen \u00e7ocuklar\u0131n bu hastal\u0131klardan daha az etkilendi\u011fini daha \u00f6nce bir\u00e7ok kez g\u00f6zlemlemi\u015fti.<\/p>\n
\u201c\u00c7iftlik etkisi\u201d olarak adland\u0131r\u0131lan bu durumun nas\u0131l ortaya \u00e7\u0131kt\u0131\u011f\u0131 ise tam olarak bilinmiyordu. Almanya\u2019daki Helmholtz M\u00fcnih ve Ludwig Maximilian \u00dcniversitesi Hastanesi \u00f6nc\u00fcl\u00fc\u011f\u00fcndeki ekip, koruyucu etkiyle ba\u011flant\u0131l\u0131 olabilecek belirli bakteri t\u00fcrlerini tespit etti. DOKUZ BAKTER\u0130 BEL\u0130RLEND\u0130Ara\u015ft\u0131rmada Almanya\u2019n\u0131n g\u00fcneyindeki k\u0131rsal b\u00f6lgelerde ya\u015fayan 1.018 okul \u00e7a\u011f\u0131ndaki \u00e7ocu\u011fun yataklar\u0131ndan al\u0131nan toz \u00f6rnekleri incelendi.<\/p>\n
\u00c7iftlikte ya\u015fayan \u00e7ocuklardan 47\u2019sinin bulundu\u011fu i\u015fletmelerdeki inek ah\u0131rlar\u0131ndan da hava \u00f6rnekleri topland\u0131. Yap\u0131lan analizler sonucunda ast\u0131m ve alerjilere kar\u015f\u0131 koruyucu etkiyle ba\u011flant\u0131l\u0131 dokuz bakteri t\u00fcr\u00fc belirlendi. Bunlar aras\u0131nda Romboutsia timonensis ve Glutamicibacter arilaitensis adl\u0131 bakteriler de bulunuyor.<\/p>\n
Ayr\u0131ca, ara\u015ft\u0131rmac\u0131lara g\u00f6re bu bakteriler, ast\u0131ma kar\u015f\u0131 g\u00f6zlenen \u00e7iftlik etkisinin yakla\u015f\u0131k \u00fc\u00e7te ikisini a\u00e7\u0131klayabiliyor. Saman nezlesi ve atopik egzama \u00fczerindeki koruyucu etkinin ise yakla\u015f\u0131k yar\u0131s\u0131yla ba\u011flant\u0131l\u0131 olabilecekleri belirtiliyor. Bakteriler, \u00e7ocuklar\u0131n yataklar\u0131ndan al\u0131nan toz \u00f6rneklerindeki toplam mikroorganizmalar\u0131n yakla\u015f\u0131k y\u00fczde 6\u2019s\u0131n\u0131 olu\u015fturdu.<\/p>\n
\u0130nek ah\u0131rlar\u0131ndan al\u0131nan hava \u00f6rneklerinde ise bu oran y\u00fczde 25\u2019e y\u00fckseldi. Edinilen bilgilere g\u00f6re, kAYNA\u011eI \u0130NEKLER OLAB\u0130L\u0130RBilim insanlar\u0131, s\u00f6z konusu bakterilerin ineklerin ba\u011f\u0131rsaklar\u0131nda ya\u015fad\u0131\u011f\u0131n\u0131 ve hayvan d\u0131\u015fk\u0131s\u0131 yoluyla ah\u0131r ortam\u0131na yay\u0131ld\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcn\u00fcyor. Ah\u0131rlardaki havaya kar\u0131\u015fan bakteriler veya bakterilerin \u00fcretti\u011fi maddeler solunum yoluyla \u00e7ocuklar\u0131n v\u00fccuduna girebiliyor.<\/p>\n
\u00c7iftlikte vakit ge\u00e7iren \u00e7ocuklar\u0131n bu mikroorganizmalar\u0131 k\u0131yafetleri ve e\u015fyalar\u0131 arac\u0131l\u0131\u011f\u0131yla evlerine ta\u015f\u0131mas\u0131 da m\u00fcmk\u00fcn g\u00f6r\u00fcl\u00fcyor. Bakterilerin \u00e7ocuklar\u0131n yataklar\u0131ndaki toz \u00f6rneklerinde bulunmas\u0131, maruziyetin yaln\u0131zca ah\u0131rla s\u0131n\u0131rl\u0131 kalmad\u0131\u011f\u0131n\u0131 g\u00f6steriyor. Buna g\u00f6re, bu mikroorganizmalarla kar\u015f\u0131la\u015fan, \u00f6zellikle de \u00e7iftliklerde ya\u015fayan \u00e7ocuklarda ast\u0131m g\u00f6r\u00fclme oran\u0131n\u0131n daha d\u00fc\u015f\u00fck oldu\u011fu belirlendi.<\/p>\n
BA\u011eI\u015eIKLIK S\u0130STEM\u0130N\u0130 E\u011e\u0130T\u0130YORAst\u0131m, saman nezlesi, egzama ve farkl\u0131 alerji t\u00fcrleri, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin normalde zarars\u0131z olan maddelere a\u015f\u0131r\u0131 tepki vermesi sonucunda ortaya \u00e7\u0131kabiliyor. Ara\u015ft\u0131rmac\u0131lara g\u00f6re \u00e7iftlik ortam\u0131ndaki bakteriler, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin bu maddelere daha dengeli tepki vermesine yard\u0131mc\u0131 olabilecek metabolitler \u00fcretiyor. Bu maddeler, h\u00fccrelerde bulunan AhR adl\u0131 bir resept\u00f6r\u00fc harekete ge\u00e7iriyor.<\/p>\n
AhR\u2019nin etkinle\u015fmesi ba\u011f\u0131\u015f\u0131kl\u0131k sinyallerini ve baz\u0131 genlerin \u00e7al\u0131\u015fma bi\u00e7imini de\u011fi\u015ftirebiliyor. Orta seviyedeki AhR etkinli\u011finin g\u00fc\u00e7l\u00fc bir iltihap kar\u015f\u0131t\u0131 tepki olu\u015fturabilece\u011fi ve b\u00f6ylece ast\u0131m ile alerjilerin geli\u015fme ihtimalini azaltabilece\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor. Ancak ara\u015ft\u0131rmac\u0131lar, etkinin maruz kal\u0131nan miktara ba\u011fl\u0131 olabilece\u011fine dikkat \u00e7ekiyor.<\/p>\n
AhR\u2019nin \u00e7ok y\u00fcksek seviyelerde etkinle\u015fmesi zararl\u0131 olabilirken, ah\u0131r havas\u0131ndaki bakteri kaynakl\u0131 maddelerin daha d\u00fc\u015f\u00fck ve dengeli bir uyar\u0131m olu\u015fturdu\u011fu de\u011ferlendiriliyor. Edinilen bilgilere g\u00f6re, nEDEN-SONU\u00c7 KANITLANMADI\u00c7al\u0131\u015fma, belirli bakterilerle ast\u0131m ve alerjilerin daha az g\u00f6r\u00fclmesi aras\u0131nda g\u00fc\u00e7l\u00fc bir ba\u011flant\u0131 ortaya koyuyor. Buna ra\u011fmen ara\u015ft\u0131rma g\u00f6zlemsel nitelikte oldu\u011fu i\u00e7in bakterilerin hastal\u0131klar\u0131 do\u011frudan \u00f6nledi\u011fini kan\u0131tlam\u0131yor.<\/p>\n
\u00c7iftliklerde b\u00fcy\u00fcyen \u00e7ocuklar\u0131n ya\u015fam bi\u00e7imi, beslenmesi, hayvanlarla temas\u0131, hava kalitesi ve genetik \u00f6zellikleri gibi ba\u015fka etkenler de sonu\u00e7lar\u0131 etkileyebilir. Bilim insanlar\u0131n\u0131n bundan sonraki a\u015famada bakterilerin ba\u011f\u0131\u015f\u0131kl\u0131k sistemi \u00fczerindeki etkisini laboratuvar ve klinik \u00e7al\u0131\u015fmalarla ayr\u0131nt\u0131l\u0131 bi\u00e7imde incelemesi gerekiyor. Bununla birlikte, ara\u015ft\u0131rmac\u0131lar, ineklerden bakterilere, ah\u0131r havas\u0131ndan \u00e7ocuklar\u0131n ba\u011f\u0131\u015f\u0131kl\u0131k sistemine uzanan zincirin ilk kez bu kadar ayr\u0131nt\u0131l\u0131 bi\u00e7imde g\u00f6sterildi\u011fini belirtiyor.<\/p>\n
Bulgular do\u011frulan\u0131rsa gelecekte \u00e7ocuklar\u0131 \u00f6zellikle ast\u0131m, saman nezlesi ve egzama gibi yayg\u0131n hastal\u0131klardan korumaya y\u00f6nelik bakteri veya bakteri metaboliti temelli son \u00f6nleyici y\u00f6ntemler geli\u015ftirilebilir. Ancak analistler, sonu\u00e7lar\u0131n \u00e7ocuklar\u0131n bilin\u00e7li olarak kirli ortamlara sokulmas\u0131 veya hijyen kurallar\u0131n\u0131n terk edilmesi gerekti\u011fi anlam\u0131na gelmedi\u011finin alt\u0131n\u0131 \u00e7iziyor.<\/p>\n","protected":false},"excerpt":{"rendered":"
\u00c7ocuklar\u0131 ast\u0131m ve alerjiden koruyan \u201c\u00e7iftlik etkisinin\u201d s\u0131rr\u0131 \u00e7\u00f6z\u00fcld\u00fc konusunda dikkat \u00e7eken geli\u015fmeler ya\u015fan\u0131yor. Beklentiler ve \u00d6ng\u00f6r\u00fcler G\u00fcncelleme Tarihi: A\u011fustos 03, 2026 14:31 \u00c7iftliklerde b\u00fcy\u00fcyen \u00e7ocuklarda ast\u0131m, saman nezlesi ve egzama gibi hastal\u0131klar\u0131n daha az g\u00f6r\u00fclmesinin nedeni y\u0131llard\u0131r ara\u015ft\u0131r\u0131l\u0131yordu. Bilim insanlar\u0131, bu do\u011fal koruyucu etkinin arkas\u0131nda bulunabilecek dokuz bakteri t\u00fcr\u00fcn\u00fc belirledi. Ancak ara\u015ft\u0131rma hen\u00fcz bu […]<\/p>\n","protected":false},"author":1,"featured_media":1717,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_is_manset":"","_is_son_dakika":"","_is_one_cikan":"","_is_gunun_secimleri":"","_is_cok_okunan":"","_is_sag_widget":"","_tanhaber_views":14,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-1716","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-teknoloji"],"_links":{"self":[{"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/1716","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=1716"}],"version-history":[{"count":0,"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/1716\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/media\/1717"}],"wp:attachment":[{"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=1716"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=1716"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bentanofficial.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=1716"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}